간행물

대한소화기학회> 대한소화기학회지

대한소화기학회지 update

The Korean Journal of Gastroenterology

  • : 대한소화기학회
  • : 의약학분야  >  내과학
  • : KCI등재
  • : SCOPUS
  • : 연속간행물
  • : 월간
  • : 1598-9992
  • : 2233-6869
  • : 대한소화기병학회잡지(~1989)→대한소화기병학회지(1990~)→대한소화기학회지(1995~)

수록정보
수록범위 : 1권1호(1968)~74권6호(2019) |수록논문 수 : 5,541
대한소화기학회지
74권6호(2019년 12월) 수록논문
최근 권호 논문
| | | |

KCI등재 SCOPUS

1염증성 장질환에서 바이오시밀러에 대한 아시아 의사들의 관점 - 우리는 사용할 준비가 되어 있는가?

저자 : 나수영 ( Soo-young Na )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 301-303 (3 pages)

다운로드

(기관인증 필요)

키워드 보기
초록보기

KCI등재 SCOPUS

2위 점막연관림프조직 림프종의 진단과 치료

저자 : 공은정 ( Eun Jeong Gong ) , 최기돈 ( Kee Don Choi )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 304-313 (10 pages)

다운로드

(기관인증 필요)

초록보기

The stomach is the most common primary site of an extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) type, which is characterized by an indolent clinical course. A diagnosis of gastric MALT lymphoma requires an endoscopic biopsy that should be confirmed by an experienced pathologist. Gastric MALT lymphoma shows a variable endoscopic appearance, including erosion, erythema, discoloration, atrophy, ulcer, and subepithelial lesion. The distribution is often multifocal. Therefore, clinical suspicion and multiple biopsies are essential for an accurate diagnosis. Gastric MALT lymphoma is almost invariably associated with a Helicobacter pylori (H. pylori) infection. H. pylori eradication therapy is the mainstay of treatment, which must be delivered to all patients regardless of the H. pylori infection status or stage. For patients who have failed to achieve remission following eradication therapy, radiotherapy or chemotherapy can be considered. Radiotherapy is an effective treatment modality for a localized stage and shows excellent outcomes. In the presence of disseminated or advanced disease, chemotherapy and/or immunotherapy with the anti-CD20 monoclonal antibody, rituximab, can be applied. Treatment should be individualized according to the stage and symptoms, as well as the patients' preference. Given that the clinical course of gastric MALT lymphoma is usually indolent, watchful waiting may be an adequate strategy in selected cases where scheduled follow-up is guaranteed. (Korean J Gastroenterol 2019;74:304-313)

KCI등재 SCOPUS

3Role of Gut Microbiota in Type 2 Diabetes Mellitus and Its Complications: Novel Insights and Potential Intervention Strategies

저자 : Birhanu Woldeamlak Ketsela Yirdaw , Belete Biadgo

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 314-320 (7 pages)

다운로드

(기관인증 필요)

초록보기

Type 2 diabetes mellitus has become one of the fastest growing public health problems worldwide. The disease is believed to involve a complex process involving genetic susceptibility and environmental factors. The human intestine harbors hundreds of trillions of bacteria, as well as bacteriophage particles, viruses, fungi, and archaea, which constitute a complex and dynamic ecosystem referred to as the gut microbiota. Increasing evidence has indicated changes in the gut microbiota composition or function in type 2 diabetic patients. An analysis of 'dysbiosis' enables the detection of alterations in the specific bacteria, clusters of bacteria, or bacterial functions associated with the occurrence of type 2 diabetes. These bacteria are involved predominantly in the control of inflammation and energy homeostasis. This review attempts to show that the gut microbiota are important factors for the occurrence of type 2 diabetes and are important for the treatment of gut microbiota dysbiosis through bariatric surgery, fecal microbiota transplantation, prebiotics, and probiotics. (Korean J Gastroenterol 2019;74:314-320)

KCI등재 SCOPUS

4위식도 역류 질환의 최신 진단 진료지침: Lyon Consensus 소개

저자 : 김태오 ( Tae-oh Kim ) , 정혜경 ( Hye-kyung Jung )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 321-325 (5 pages)

다운로드

(기관인증 필요)

초록보기

Gastroesophageal reflux disease (GERD) is diagnosed according to the medical history or in response to proton pump inhibitor therapy. However, the need for further testing is always appropriate. The decisive evidence for the current diagnosis of GERD is severe erosive esophagitis of Los Angeles grade C or D, long-segment Barrett's mucosa or peptic strictures seen on endoscopy or an acid exposure time >6% on ambulatory pH or pH impedance monitoring. If ambulatory reflux monitoring correlates between reflux and the symptoms, then the diagnosis and treatment are certain. If it is difficult to clearly diagnose this malady as seen upon endoscopy and ph/pH impedance monitoring, then this review recommends the biopsy findings, motor evaluation and novel impedance metrics. Novel impedance metrics include the baseline impedance and the post reflux swallow-induced peristaltic wave index. Therefore, making a future GERD diagnosis should focus on defining the patient's phenotype. The phenotype is determined by the level of reflux exposure, clearance efficacy, anatomy of the esophageal gastric junction, and the psychological state of the patient. The purpose of this review is to clarify the diagnostic guideline for GERD according to several test methods. (Korean J Gastroenterol 2019;74:321-325)

KCI등재 SCOPUS

5대장 폴립절제술 후 예방적 클립 사용 없이 발생한 지연 출혈: 단일기관에서의 관찰 연구

저자 : 김현진 ( Hyeonjin Kim ) , 김재현 ( Jae Hyun Kim ) , 최윤정 ( Youn Jung Choi ) , 권혜정 ( Hye Jung Kwon ) , 장희경 ( Hee Kyung Chang ) , 김성은 ( Sung Eun Kim ) , 문원 ( Won Moon ) , 박무인 ( Moo In Park ) , 박선자 ( Seun Ja Park )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 326-332 (7 pages)

다운로드

(기관인증 필요)

초록보기

Background/Aims: Bleeding is one of the major complications of a colorectal polypectomy. The aim of this study was to identify the risk of delayed bleeding, particularly after a colorectal endoscopic mucosal resection (EMR) without prophylactic clipping.
Methods: Between April 2014 and August 2014, patients who underwent colorectal EMR (≥6 mm and <2 cm) without prophylactic clipping were included. This study evaluated the incidence of delayed bleeding and the associated factors after colorectal EMR without prophylactic clipping.
Results: A total of 717 colorectal polyps (≥6 mm and <2 cm) of 243 patients resected by colorectal EMR in the study period were evaluated. The mean age of the patients was 63 years; 165 patients were men and 78 patients were women. The mean polyp size removed by colorectal EMR was 9.0 mm (range 6.0-19.0), and the number of polyps larger than 1 cm was 212 (29.6%). Delayed bleeding after colorectal EMR occurred in 12 polyps (1.7%) in eight patients (3.3%), and there were no significant risk factors affecting delayed bleeding.
Conclusions: This study identified that the incidence of delayed bleeding on colorectal polyps (≥6 mm and <2 cm) after EMR without prophylactic clipping was 3.3%, but no significant risk factors affecting delayed bleeding were found. (Korean J Gastroenterol 2019;74:326-332)

KCI등재 SCOPUS

6아시아 의사들의 바이오시밀러 단일 클론 항체에 대한 지식과 관점: 유럽 의사들과 비교

저자 : 박수경 ( Soo-kyung Park ) , 문원 ( Won Moon ) , 김은수 ( Eun Soo Kim ) , 박상현 ( Sang Hyun Park ) , 박동일 ( Dong Il Park )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 333-346 (14 pages)

다운로드

(기관인증 필요)

초록보기

Background/Aims: Current knowledge and viewpoints regarding biosimilars among physicians in Asia are unknown, even though these were investigated by European Crohn's and Colitis Organization (ECCO) members in 2013 and 2015. Thus, this study conducted a multinational survey to assess the awareness of biosimilar monoclonal antibodies among Asian physicians.
Methods: A 17-question multiple-choice anonymous web survey was conducted with the logistic support of the Asian Organization of Crohn's and Colitis (AOCC). Randomly selected AOCC members were invited by e-mail to participate between February 24, 2017 and March 26, 2017.
Results: In total, 151 physicians from eight Asian countries responded to the survey. Most of the participants were gastroenterologists (96.6%), and 77.5% had cared for inflammatory bowel diseases (IBD) patients for more than 5 years. The majority of the respondents (66.2%) were aware that a biosimilar is similar but not equivalent to the originator. The majority of respondents (77.5%) considered cost saving to be the main advantage of biosimilars, but a high percentage of respondents (38.4%) were concerned about a different immunogenicity from that of the originator (92.4% and 27.1% respectively in ECCO 2015). Only 19.2% considered that the originator and biosimilars were interchangeable, and only 6.0% felt very confident in the use of biosimilars (44.4% and 28.8% respectively in ECCO 2015).
Conclusions: Asian gastroenterologists in 2017 are generally well informed about biosimilars. On the other hand, compared to the ECCO members surveyed in 2015, Asian gastroenterologists had more concerns and less confidence about the use of biosimilars in clinical practice. Thus, IBD-specific data on the comparison of the efficacy, safety, and immunogenicity in Asian patients are needed. (Korean J Gastroenterol 2019;74:333-340)

KCI등재 SCOPUS

7만성 B형간염, 비알코올성 지방간 질환 환자에서 혈청 Asialo-α1-acid Glycoprotein의 진행성 간섬유화, 간경변증 예측력 연구

저자 : 김승업 ( Seung Up Kim ) , 전미영 ( Mi Young Jeon ) , 임태섭 ( Tae Seop Lim )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 341-348 (8 pages)

다운로드

(기관인증 필요)

초록보기

Background/Aims: The utility of asialo-α1-acid glycoprotein (AsAGP) for assessing the fibrotic burden is unknown. This study examined the diagnostic performance of the AsAGP level for advanced liver fibrosis or cirrhosis in patients with chronic hepatitis B (CHB) or nonalcoholic fatty liver disease (NAFLD).
Methods: From July to December 2018, 48 patients with CHB and 75 with NAFLD were recruited prospectively. Transient elastography was used as the reference standard for liver fibrosis, and the cutoff liver stiffness values were defined as 10.0 kilopascal (kPa) for ≥F3 and 12.0 kPa for F4 in CHB patients, and 9.0 kPa for ≥F3 and 11.8 kPa for F4 in NAFLD patients.
Results: To predict stage ≥F3 and F4 fibrosis, the areas under the receiver operating characteristic curves of the AsAGP level in patients with CHB were 0.788 (95% CI 0.647-0.930; p=0.005) and 0.825 (95% CI 0.674-0.976; p=0.004), respectively. The cutoff AsAGP levels in patients with CHB that maximized the sum of the sensitivity and specificity values were 1.31 (sensitivity 100.0%, specificity 52.6%) and 1.55 (sensitivity 75.0%, specificity 80.0%), respectively. In contrast, the AsAGP level was similar regardless of the fibrosis stage in patients with NAFLD (all p>0.05 between the stages).
Conclusions: The AsAGP level showed acceptable diagnostic accuracy in predicting advanced liver fibrosis and cirrhosis in patients with CHB but not in those with NAFLD. Further studies will be needed to validate the diagnostic performance of the AsAGP level in patients with NALFD. (Korean J Gastroenterol 2019;74:341-348)

KCI등재 SCOPUS

8같은 종양에서 깊이에 따라 분포된 혼합형 신경내분비-비신경내분비 암의 증례: 2010년 세계보건기구에서 정의한 혼합형 샘-신경내분비 암 정의에 부합하지 않는 암

저자 : 정준호 ( Joonnho Jeong ) , 정경원 ( Kyoungwon Jung ) , 김재현 ( Jae Hyun Kim ) , 김성은 ( Sung Eun Kim ) , 문원 ( Won Moon ) , 박무인 ( Moo In Park ) , 박선자 ( Seun Ja Park )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 349-355 (7 pages)

다운로드

(기관인증 필요)

초록보기

A mixed adenoneuroendocrine carcinoma (MANEC) of the stomach is a rare disease entity that was first defined by the World Health Organization (WHO) classification (2010) for tumors of the digestive system. According to the WHO classification (2010), MANEC is referred to as a tumor with both neuroendocrine and non-neuroendocrine neoplasms; each component of the tumor should be at least 30%. On the other hand, this cut-off value lacks clinical evidence and does not explain the characteristics and heterogeneity of this tumor. A 66-year-old male diagnosed with early gastric cancer (EGC) at a community hospital was referred to the Kosin University Gospel Hospital for further evaluation of gastric cancer. Esophagogastroduodenoscopy and EUS performed at the Kosin University Gospel Hospital revealed a sub-mucosal tumor-like component. In addition, a re-biopsy revealed a neuroendorine tumor at different depths of the same tumor. The final pathologic-diagnosis through surgery revealed a mixed neuroendocrine- non-neuroendocrine neoplasm, which is inconsistent with the definition of MANEC. Clinicians should consider EUS when a tumor has atypical endoscopic findings, even if EGC has already been diagnosed. (Korean J Gastroenterol 2019;74:349 -355)

KCI등재 SCOPUS

9담도선섬유종의 자기공명영상 소견

저자 : 이선영 ( Sunyoung Lee ) , 김경원 ( Kyoung Won Kim ) , 정우경 ( Woo Kyoung Jeong ) , 유은실 ( Eunsil Yu ) , 장기택 ( Kee-taek Jang )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 356-361 (6 pages)

다운로드

(기관인증 필요)

초록보기

Biliary adenofibroma is a rare tumor with a bile duct origin characterized by a complex tubulocystic non-mucin secreting biliary epithelium with abundant fibrous stroma. The MRI features of biliary adenofibroma are not well established. The authors encountered two patients with biliary adenofibroma and reviewed the literature focusing on the MRI findings. A well-circumscribed multicystic tumor with septal enhancement and no intrahepatic bile duct communication may be the characteristic MRI findings of biliary adenofibroma. (Korean J Gastroenterol 2019;74:356-361)

KCI등재 SCOPUS

10상부위장관 대량 출혈로 나타난 췌장 가성낭종

저자 : 양서희 ( Seo Hee Yang ) , 손준혁 ( Jun Hyuk Son ) , 이윤석 ( Yoon Suk Lee )

발행기관 : 대한소화기학회 간행물 : 대한소화기학회지 74권 6호 발행 연도 : 2019 페이지 : pp. 362-364 (3 pages)

다운로드

(기관인증 필요)

키워드 보기
초록보기
12
권호별 보기
가장 많이 인용된 논문

(자료제공: 네이버학술정보)

가장 많이 인용된 논문
| | | |
1연안해역에서 석유오염물질의 세균학적 분해에 관한 연구

(2006)홍길동 외 1명심리학41회 피인용

다운로드

2미국의 비트코인 규제

(2006)홍길동심리학41회 피인용

다운로드

가장 많이 참고한 논문

(자료제공: 네이버학술정보)

가장 많이 참고한 논문

다운로드

2미국의 비트코인 규제

(2006)홍길동41회 피인용

다운로드

해당 간행물 관심 구독기관

연세대학교 경희대학교 아주대학교 서울대학교 부산대학교
 39
 34
 31
 29
 28
  • 1 연세대학교 (39건)
  • 2 경희대학교 (34건)
  • 3 아주대학교 (31건)
  • 4 서울대학교 (29건)
  • 5 부산대학교 (28건)
  • 6 고려대학교 (26건)
  • 7 중원대학교 (23건)
  • 8 진주보건대학교 (21건)
  • 9 단국대학교 (20건)
  • 10 인제대학교 (15건)

내가 찾은 최근 검색어

최근 열람 자료

맞춤 논문

보관함

내 보관함
공유한 보관함

1:1문의

닫기