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당뇨병(JKD) update

The Journal of Korean Diabetes

  • : 대한당뇨병학회
  • : 의약학분야  >  내과학
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  • : 임상 당뇨병(~2010)→ 당뇨병(JKD)(2011~)

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수록범위 : 1권1호(2000)~18권4호(2017) |수록논문 수 : 847
당뇨병(JKD)
18권4호(2017년) 수록논문
최근 권호 논문
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1시론 : 건강기능식품제도, 폐지할 때가 되었다

저자 : 명승권 ( Seung-kwon Myung )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 205-213 (9 pages)

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According to a 2017 report from the Ministry of Food and Drug Safety of Korea (MFDS), the production quantity of health functional foods has increased by 29.9% from 1.133 trillion won in 2015 to 1.472 trillion won in 2016. Also, many people believe that such foods are beneficial for our health, and industries are advertising them and promoting sales under approval from the MFDS. However, the health functional foods system in Korea has important problems and flaws in terms of the definition and functional grading of health functional foods. Further, when thoroughly reviewed based on the recent literature, there is insufficient evidence to support the use of health functional foods. Therefore, it is time to repeal the Law for Health Functional Foods.

2Statement : 당뇨병성 신증 치료의 최신 지견

저자 : 기연경 ( Youn Kyung Kee ) , 한승혁 ( Seung Hyeok Han )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 214-228 (15 pages)

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Diabetic nephropathy is a common complication of diabetes mellitus and is the leading cause of chronic kidney disease. Glycemic and blood pressure control constitute the main strategies of diabetic nephropathy prevention and treatment. However, despite current therapies, nephropathy progresses to renal failure and end-stage renal disease in many patients. Therefore, new therapeutic strategies targeting different pathophysiological mechanisms are needed. This review article briefly summarizes the standard therapy for diabetic nephropathy and also describes recent advances in potential renoprotective agents that could be used to prevent the development or progression of diabetic nephropathy.

3특집 : 당뇨병 환자의 비만 관리

저자 : 이민진 ( Min Jin Lee ) , 김상수 ( Sang Soo Kim )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 229-238 (10 pages)

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Both obesity and diabetes impose not only individual health problems, but also large socioeconomic burdens worldwide. Obesity is a major cause of insulin resistance and diabetes and is closely linked to a series of microvascular and macrovascular complications that ultimately lead to increased morbidity and mortality. According to recent national survey data in Korea, obesity affects about 50% of adults with type 2 diabetes mellitus. Given the evidence that anti-obesity management has been beneficial in the treatment for patients with type 2 diabetes mellitus and obesity, providers should establish a strategy for weight loss for optimal, comprehensive patient management. Lifestyle intervention including diet and exercise is the cornerstone of prevention and management for obesity and type 2 diabetes mellitus. Antiobesity drugs should be provided to those who do not respond appropriately to lifestyle intervention. Emerging data support the superiority of metabolic surgery over lifestyle or medical management for the management of type 2 diabetes associated with severe obesity. This article concisely reviews the current recommendation for lifestyle intervention including diet and exercise and pharmacological and surgical methods for obesity management in type 2 diabetic patients.

4특집 : 당뇨병과 근감소증

저자 : 김동현 ( Dong Hyun Kim ) , 유태양 ( Tae Yang Yu )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 239-247 (9 pages)

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Sarcopenia is defined as the loss of muscle mass and strength that occurs with aging. Although the etiology, pathogenesis, and diagnosis of sarcopenia are obscure, sarcopenia has been suggested to play a pivotal role in the pathogenesis of frailty and functional impairment in diabetes. The aim of this article was to provide an overview of the pathogenesis, diagnosis, epidemiology, and clinical implications of sarcopenia and the relationship between diabetes and sarcopenia.

5특집 : 당뇨병과 골다공증

저자 : 진흥용 ( Heung Yong Jin )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 248-252 (5 pages)

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Diabetes mellitus, which is a well-known chronic metabolic disorder with diverse complications, affects over 10% and up to nearly 20% of older adults; its prevalence is increasing rapidly. Fracture is also important issue in a large proportion of older adults and osteoporosis is a common cause of fracture. Therefore, both diabetes and increased fracture risks due to osteoporosis have become serious concerns and health problems in aging societies these days. However, the mechanisms of and exact relationship between diabetes and bone conditions are not fully understood and remain controversial issues because observational and animal studies do not show consistent results. Nonetheless, we should not overlook that bone quality and fractures are also important in older diabetic patients just as in the non-diabetic general population. Therefore, we need a better understanding of how diabetes and its treatment relate to bone health; this will improve morbidity and mortality in older diabetic and osteoporosis patients. Until these questions are answered, we should continue treating diabetic patients for osteoporosis with wellknown current medications to improve bone mineral density besides including optimal glucose control and management of micro and macro vascular complications.

6특집 : 당뇨병 환자의 피부질환

저자 : 김민성 ( Min Sung Kim )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 253-258 (6 pages)

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Diabetes mellitus (DM) is a metabolic disease characterized by relative or absolute insulin deficiency. The hyperglycemic state of DM leads to changes in practically every cell type and organ of the human body. As skin changes can manifest before onset of DM, they might have diagnostic relevance. Some skin disorders are highly associated with increased risk of important outcomes, such as skin lesions, ulcerations, and diabetic foot, which can be associated with significantly increased morbidity and mortality of DM patients. Disease control, early-stage treatment (e.g., skin hydration, orthotic devices), and awareness of skin disorders can reduce morbidity of DM patients. Thus, better understanding of the burden of skin disorders in DM patients can help to improve the quality of life of them. The purpose of this study is to review the literature to evaluate the main clinical characteristics and complications of skin disorders in diabetic patients.

7당뇨병 교육을 위한 정보광장 : 당뇨병 환자의 약물복용 이행도 높이기

저자 : 나영 ( Young Na )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 259-263 (5 pages)

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The ultimate goal of health care providers in treating chronic diseases such as diabetes is to prevent complications by providing symptom relief and delaying disease exacerbation rather than curing the disease. For this, lifestyle habits such as eating habits, smoking, drinking, and exercise should be improved and drug therapy should be continuously implemented. For patient management and treatment, medication adherence affects disease progression, and long-term outcomes. Therefore, poor medication adherence will lead to exacerbation of the disease; as a result, the incidence of complications increases and medical costs increase. Although the first diagnosis of diabetes is important, it is more important to continue to care for and manage patients, so we are looking for ways to improve patient medication adherence.

8당뇨병 교육을 위한 정보광장 : 당뇨병 환자의 건강한 외식하기

저자 : 이해영 ( Hae-young Lee )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 264-269 (6 pages)

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Dining out can be difficult for diabetics whose dietary choices are limited compared to healthy people. However, it is almost impossible to eat only at home in modern society, so it is essential to learn and practice how to eat well. As mentioned above, the nutrition labeling system is being applied and extended not only to processed foods, but also to restaurants, and there are many restaurants that present calories and major nutrients of their food options, although the nutrient names can differ depending on location. Therefore, diabetes patients can enjoy eating out if they can check the nutritional information, decide a menu to suit their nutritional needs, and limit the amount of food eaten. For sugar reduction, it is important to limit added sugars, particularly by selecting proper beverages. It should not be forgotten that sodium intake is easy to fall into the temptation to eat sugars as a compensation for salty taste and can cause complications such as hypertension. Also, it is advisable for diabetics to visit restaurants offering low-salt options.

9당뇨병 교육을 위한 정보광장 : 당뇨병 환자의 삶의 경험: 국내 질적 연구를 중심으로

저자 : 유빈 ( Been Yoo )

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 270-274 (5 pages)

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Qualitative research methodology has become more recognized and valued in diabetes behavioral research in recent years. Qualitative research is very rare in Korea, especially for diabetes; on the other hand, qualitative research is increasing abroad. This paper reviews qualitative research on the life experiences of diabetes patients in Korea. Drawing on advanced research, it is helpful to know the essence of such experiences and the exact phenomena diabetes patients face as revealed in their own voices. Also, understanding of and interest in the subjective experiences of diabetes patients will inform the development of new intervention methods.

10원저 : 당뇨병 환자에서 Dapagliflozin 투여 전후의 혈당변화: 단일 기관 신약 안전성 모니터 결과

저자 : 이형우 ( Hyung Woo Lee ) , 문선준 ( Sun Joon Moon ) , 한희심 ( Hee Sim Han ) , 신은정 ( Eun

발행기관 : 대한당뇨병학회 간행물 : 당뇨병(JKD) 18권 4호 발행 연도 : 2017 페이지 : pp. 275-283 (9 pages)

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Background: Dapagliflozin, a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor, lowers blood glucose by reducing glucose reabsorption at the proximal renal tubule in an insulin-independent manner. We aimed to evaluate the efficacy and safety of dapagliflozin and to identify the risk factors of adverse drug events in patients with type 2 diabetes. Methods: As an institutional pharmacovigilance review activity, we reviewed data from medical records of 455 patients with type 2 diabetes who received dapagliflozin therapy from July 2014 to August 2015 in Seoul National University Hospital. We analyzed the changes in laboratory data and examined the characteristics of dapagliflozin users who showed adverse effects. Results: Mean changes in HbA1c and fasting serum glucose level from baseline to second visit were -0.42% (8.07 ± 1.51% to 7.65 ± 1.31%, P < 0.001) and -22.9 mg/dL (167.8 ± 48.5 mg/dL to 144.9 ± 37.6 mg/dL, P < 0.001), respectively. Adverse drug events observed during this study were lower urinary tract symptoms (7.7%), dehydration-related symptoms (6.1%), ketonuria (3.4%), hypoglycemia (3.4%), and urogenital infection (4.2%). Thiazide use, age, insulin use, number of anti-diabetic drugs, gender and history of urogenital infection were the risk factors for adverse drug events (P < 0.05). Conclusion: Dapagliflozin significantly improved hyperglycemia in patients with type 2 diabetes without serious adverse drug events. The incidences of adverse drug events were was similar to those ofthat in the previous studies.

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