Diabetes is a very common disease in cirrhosis. The pathogenesis of diabetes mellitus in cirrhosis is poorly studied, but is currently known to be due to insulin resistance and decreased pancreatic β-cell function. Diabetes interacts with cirrhosis. Diabetes has a negative effect on the progression and prognosis of cirrhosis, and cirrhosis also worsens diabetes. Diabetes mellitus in patients with cirrhosis is difficult to diagnose because it is latent in many cases with normal fasting blood glucose, and can be diagnosed only by glucose tolerance test. Considering the interrelationship between cirrhosis and diabetes, it is very important to control and treat diabetes. However, there is still a small amount of clinical interest and research and often stays in conventional treatment. This review will overview the relationship between cirrhosis and diabetes and suggest future research directions.