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한방재활의학과학회> 한방재활의학과학회지

한방재활의학과학회지 update

Journal of oriental rehabilitation medicine

  • : 한방재활의학과학회
  • : 의약학분야  >  재활의학
  • : KCI등재
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  • : 연속간행물
  • : 계간
  • : 1229-1854
  • : 2288-4114
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수록정보
수록범위 : 1권1호(1991)~30권4호(2020) |수록논문 수 : 1,449
한방재활의학과학회지
30권4호(2020년 10월) 수록논문
최근 권호 논문
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KCI등재

1경골 파혈산동탕(破血散疼湯)이 골절 생쥐의 골 유합에 미치는 영향

저자 : 신우석 ( Woo-suk Shin ) , Kira Parichuk , 차윤엽 ( Yun-yeop Cha )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 1-16 (16 pages)

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Objectives The main purpose of this study was to evaluate the bone healing effect of Pahyeolsandong-tang (PHT)(Poxiesanteng-tang) extract in tibia fracture-induced mice.
Methods PHT was extracted using a solution of 35% ethanol in 60°C for 8 hours. Mice were randomly divided into 4 groups (normal, control, PHT 50 and PHT 100). Mice of experimental groups were medicated with PHT 50 or 100 mg/kg for 7 to 21 days. To clarify the effect of bone fracture healing, relative messenger RNA (mRNA) expressions of osteocalcin (OCN), runt-related transcription factor 2 (Runx2), osterix (OSX), Sox9, collagen type Ⅱ alpha 1 chain (Col2a1), receptor activator of nuclear factor kappa-B ligand (RANKL), osteoprotegerin (OPG) were examined.
Results In in vitro experiment, relative mRNA expression of OCN, Runx2, Col2a1 was significantly increased in PHT treated group to compare with control differentiation group. In in vivo experiment, relative mRNA expression of OCN, Runx2, OSX, Sox9, Col2a1, RANKL, OPG was significantly increased in PHT treated group.
Conclusions This study showed that PHT accelerates bone fracture healing through the activation of osteoclasts and osteoblasts. It was showed that PHT significantly promotes osteoblasts differentiation by osteoblast differentiation markers such as OCN, Runx2, Col1a2. Also it was investigated that PHT had stimulatory effect on osteoblasts function through enhancing OCN, Runx2, OSX, Sox9, Col2a1 and, osteoclasts function through enhancing RANKL and OPG markers. PHT effectively promotes bone fracture healing process through activation of osteoblasts and osteoclasts. (J Korean Med Rehabil 2020;30(4):1-16)

KCI등재

2육미지황탕(六味地黃湯)이 대퇴골절 동물모델의 골절 유합인자 및 형태학적 변화에 미치는 영향

저자 : 김현석 ( Hyun-seok Kim ) , 전동휘 ( Dong Hwi Jeon ) , 오민석 ( Min-seok Oh )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 17-30 (14 pages)

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Objectives The purpose of this study is to evaluate the healing effect of Yukmijihwangtang (YM) on femur fractured mice.
Methods Mice were randomly divided into 6 groups: normal, control, positive control, YM with low, medium, high dosage each. All groups were prepared with femur fracture and treated diffrently. In order to measure bone regeneration effects, we analysed the levels of cyclooxygenase-2 (COX2), bone morphogenetic protein-2 (BMP2), collagen type Ⅱ alpha 1 chain (Col2a1), Sox9, runt-related transcription factor 2 (Runx2), and osterix genes expressed in bone. For morphological analysis, muscles were removed and femur was observed with naked eye.
Results COX2 gene expression in bone marrow significantly decreased. BMP2 gene expression significantly increased. Col2a1 gene expression significantly increased. Sox9 gene expression increased as well. Runx2 gene expression in bone marrow increased, but there was no statistical significance. Osterix gene expression significantly increased. Union of the fracture site progressed more in YM group compared to the control group. The fracture union score was significantly decreased in YM group compared to the control group.
Conclusions YM showed anti-inflammatory effect, promoted bone regeneration by stimulating the bone regeneration factor. In conclusion, YM can help fracture healing and it well be applied clinically to patients with fracture. (J Korean Med Rehabil 2020;30(4):17-30)

KCI등재

3추출법에 따른 당귀수산과 작약감초탕의 성분과 활성의 비교

저자 : 이대연 ( Dae-yeon Lee ) , 이호성 ( Ho-sung Lee ) , 조주휘 ( Ju-hwi Jo ) , 이영우 ( Young-woo Yi ) , 김성진 ( Sung-jin Kim ) , 강경래 ( Kyungrae Kang ) , 권태욱 ( Tae-wook Kwon ) , 양승구 ( Seung Gu Yang ) , 이인희 ( In-hee Lee )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 31-39 (9 pages)

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Objectives Danggwisoo-san and Jakyakgamcho-tang are frequently prescribed for traffic accident patients in Korea. The aim of this study was to examine index compound analysis, antioxidant activity and amount of starch measurement by extraction method.
Methods Danggwisoo-san and Jakyakgamcho-tang were extracted with water and 70% ethanol. Antioxidant activity was measured by 2,2-Diphenyl-1-picrylhydrazyl, 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and ferric reducing antioxidant power according to the standard protocol. The contents of the indicator components nodakenin, paeoniflorin, and glycyrrhizin were measured by high-performance liquid chromatography, respectively. All starches were hydrolyzed and then total D-glucose was measured and compared.
Results Antioxidant activity was excellent in 70% ethanol in all assays. The index component was jagged because its solubility was different depending on the extraction solvent. Starch content was significantly lower in 70% alcohol extract than water extract.
Conclusions The results of this study showed that physiological activities and components are different according to extraction conditions. Each herbal medicine has a suitable extraction solvent. Also, the difference in starch content is an object to be considered as it may affect digestion and absorption. (J Korean Med Rehabil 2020;30(4):31-39)

KCI등재

4실비산의 항산화 및 지방축적 억제 효과

저자 : 김건우 ( Geon-woo Kim ) , 우창훈 ( Chang-Hoon Woo ) , 김영준 ( Young-Jun Kim ) , 안희덕 ( Hee-Duk An )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 41-53 (13 pages)

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Objectives The purpose of this study was to investigate the effects of Silbi-san on the antioxidant and fat accumulation inhibition and to analyze the anti-obesity effect by analyzing the changes in serum lipid composition in obese mice.
Methods We compared contents of phytochemicals like total polyphenols and total flavonoid and antioxidant activities such as 2,2-dipheny-1-picrylhydrazyl and 2.2'-azino- bis (3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging activity. After Silbi-san in 3T3-L1 cells in vitro and mouse adipose tissue ex vivo, we quantified intracellular triglyceride accumulation and lipolysis. Moreover, the anti-obesity activity though inhibiting pancreatic lipase were analyzed. In 3T3-L1 cells, morphological changes showed that control cells had many lipid while cells treated with Silbi-san had less lipid accumulation. 30% EtOH Silbi-san treatment also suppressed the fat absorption by inhibiting the activity of pancreatic lipase and led to high lipolysis through promoting glycerol release. The experimental group was divided into four groups: Normal group fed normal feed, Control group fed 60% high fat diet (HFD) and distilled water, drug group fed 60% high fat diet and 200 mg/kg of Silbi-san water extract, drug group fed 60% HFD and 200 mg/kg of Silbi-san 30% ethanol extract.
Results Serum total cholesterol content and serum low density lipoprotein-cholesterol content were significantly decreased in the Silbi-san extract group compared to the control group, serum high density lipoprotein-cholesterol content was significantly increased in Silbi-san extract group.
Conclusions In this study, the antioxidant and fat accumulation inhibitory effects of Silbi-san were confirmed. (J Korean Med Rehabil 2020;30(4):41-53)

KCI등재

5특발성 척추측만증의 한의학적 치료에 대한 국내 연구 동향: 국내 학술지를 중심으로

저자 : 이상운 ( Sang-woon Lee ) , 추희영 ( Hui-yeong Chu ) , 김호 ( Ho Kim ) , 이상건 ( Sang-gun Lee ) , 최재용 ( Jae-yong Choi ) , 이유진 ( Yu-jin Lee ) , 최강의 ( Kang-eah Choi )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 55-64 (10 pages)

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Objectives This study aimed to analyze the trends of Korean traditional medicine treatment for idiopathic scoliosis.
Methods We searched clinical studies used Korean traditional medicine for idiopathic scoliosis in 4 Korean online databases 'Koreanstudies Information Service System', 'Earticle', 'Oriental Medicine Advanced Searching Integrated System', 'Research Information Sharing Service'. We selected 18 studies and analyzed their characteristics according to author, publication year, number/sex/age of patient, treatment period, intervention, outcome measure and result.
Results Eighteen case report studies were selected by criteria and randomized controlled trials were not found. The most frequently used therapy was Chuna therapy. Cobb's angle was most commonly used outcome measure.
Conclusions In this study, we reviewed studies used Korean traditional medicine treatments for idiopathic scoliosis. However, evidence is limited because all selected studies were case reports. This study suggests that further clinical studies are needed to provide higher evidence about Korean traditional medicine treatment for idiopathic scoliosis. (J Korean Med Rehabil 2020;30(4):55-64)

KCI등재

6척추전방전위증의 추나 치료에 대한 체계적 문헌 고찰 및 메타 분석

저자 : 홍수민 ( Su Min Hong ) , 하현주 ( Hyun Ju Ha ) , 윤광식 ( Kwang Sik Yoon )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 65-77 (13 pages)

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Objectives This study is aimed to evaluate the effectiveness of Chuna therapy for spondylolisthesis.
Methods We searched th following 10 online databases without a language restriction (National Digital Science Library [NDSL], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS], KMBASE, MEDLINE/ PubMed, Cochrane library, Ebscohost, EMBASE, Ovid, China National Knowledge Infrastru [CNKI]) to find randomized controlled trials that used Chuna therapy for spondylolisthesis. The methodological quality of each randomized controlled clinical trial was assessed using the Cochrane risk of bias tool and meta-analyses were perfomed.
Results Eleven randomized controlled trials were included. Chuna therapy showed statistically significant reduction of symptoms. Meta-analysis showed positive results for Chuna therapy for spondylolisthesis in terms of therapeutic effects to traction, chinese medicine, therapeutic exercise.
Conclusion In this study, we reviewed studies about Chuna therapy used for spondylolisthesis. The studies showed that Chuna therapy can significantly effective on spondylolisthesis. But according to Cochrane risk of bias evaluation method, most of the studies's risk of bias were unclear. Therefore, more high-quality studies will be needed. (J Korean Med Rehabil 2020;30(4):65-77)

KCI등재

7강직성 척추염의 침 치료에 대한 최근 연구동향 분석: China National Knowledge Infrastructure 검색을 중심으로

저자 : 유재은 ( Jae-eun Yu ) , 권용수 ( Yong-su Kwon ) , 김효준 ( Hyo-jun Kim ) , 박주언 ( Joon Park ) , 김국범 ( Gook-beom Kim ) , 이희원 ( Hee-won Lee ) , 배준효 ( Jun-hyo Bae )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 79-88 (10 pages)

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Objectives This study was performed to research the trends of Chinese acupuncture treatment for ankylosing spondylitis (AS).
Methods We searched clinical studies about Chinese acupuncture treatment for AS through China National Knowledge Infrastructure. We analyzed the characteristics of selected studies according to research design, sample size, publication year, treatment methods, evaluation criteria and adverse events.
Results 16 studies published from 2015 to 2020 were selected. They consisted of 11 randomized controlled trials and 5 case reports. In these studies, several types of acupuncture treatments were performed and especially there were many treatments that applied thermal stimulation of needles. The most commonly used evaluation criteria was effective rate.
Conclusions This study showed that acupuncture treatment could be effective for AS. It suggested that various studies should be conducted to provide reliable evidence about acupuncture treatment for AS in Korea. (J Korean Med Rehabil 2020;30(4):79-88)

KCI등재

8한국에서 비만 치료에 쓰이는 한약에 대한 연구 동향 보고: 2015년부터 2019년까지의 국내외 논문을 중심으로

저자 : 김수전 ( Soo-jeon Kim ) , 서연호 ( Yeon-ho Seo ) , 이한솔 ( Han-sol Lee ) , 장호경 ( Ho-kyung Chang ) , 조재흥 ( Jae-heung Cho ) , 김고운 ( Koh-woon Kim ) , 송미연 ( Mi-yeon Song )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 89-103 (15 pages)

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Objectives This study has been conducted to verify frequently used herbs and herbal formulas to treat obesity in Korea during 2015 to 2019.
Methods Publications related to treatment of obesity using herbal medicines from 2015 to 2019 were retrieved from 12 databases (PubMed, EMBASE, Scopus, China National Knowledge Infrastructure [CNKI], Koreanstudies Information Service System [KISS], National Digital Science Library [NDSL], Research Information Sharing Service [RISS], DBPIA, KMBASE, KoreaMed, KoreanTK, Oriental Medicine Advanced Searching Integrated System [OASIS]). Extracted articles were analyzed in terms of publication year, journal, and type of herbs.
Results A total of 136 studies have been included in this study. 33 herbal formulaes and 129 herbs have been analyzed. Taeyeumjowui-tang was the most frequently studied herbal formulae and Ephedrae Herba was the most frequently studied herb. Ginseng Radix was the most frequently studied single herb in isolation from herbal formulae.
Conclusions These results suggest that various herbs and herbal formulae can be used to treat obesity. Since this study includes every type of study, additional studies based on clinic are thought to be necessary. (J Korean Med Rehabil 2020;30(4):89-103)

KCI등재

9고관절 치환술 환자에 적용한 전침치료: 체계적 문헌고찰 및 메타분석

저자 : 오은미 ( Eun-mi Oh ) , 홍수민 ( Su Min Hong ) , 김호걸 ( Ho-geol Kim ) , 이은정 ( Eun-jung Lee )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 105-117 (13 pages)

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Objectives The objective of this study is to assess the effectiveness of electroacupuncture for patients with hip arthroplasty.
Methods According to participants, intervention, comparison, outcome, study design, we searched for clinical studies that conducted electroacupuncture for patients with hip arthroplasty.
Results Finally 11 randomized controlled trials were chosen for systemic review and meta-analysis. The frequently used evaluation tools were Incidence of postoperative cognitive dysfunction (POCD), heart rate, blood pressure. Almost studies showed electroacupuncture has effects for patients with hip arthroplasty. Through meta analysis, Electoacupuncture showed statistically significant effect of reducing the anesthetic dosage and incidence of postoperative psychonosema and adverse reactions in intra-operation period, reducing the incidence of POCD in peri-operation period, incidence of deep venous thrombosis in post-operation period.
Conclusion 11 studies reported that electroacupuncture has significant effects on hip arthroplasty. But, many studies were assessed in a probable high risk of bias. And all studies published in one overseas country. So, it requires attention to comprehend this study. To make up for this limitaion, more well designed clinical research are needed. (J Korean Med Rehabil 2020;30(4):105-117)

KCI등재

10수근관 증후군의 최근 6년간의 연구 동향 분석: China National Knowledge Ingrastructure (CNKI) 보고 연구를 중심으로

저자 : 전현아 ( Hyun-a Jeon ) , 신원빈 ( Won-bin Shin ) , 임수연 ( Su-yeon Lim ) , 문영주 ( Young-joo Moon ) , 이지연 ( Ji-yun Lee ) , 구승혁 ( Seung-hyeok Ku ) , 김성현 ( Sung-hyun Kim ) , 문현우 ( Hyun-woo Moon )

발행기관 : 한방재활의학과학회 간행물 : 한방재활의학과학회지 30권 4호 발행 연도 : 2020 페이지 : pp. 119-132 (14 pages)

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Objective The purpose of this study was to investigate clinical studies between 2015 and 2020 on the traditional Chinese medicine treatment for carpal tunnel syndrome (CTS) using the China National Knowledge Infrastructure (CNKI) database.
Methods We searched clinical studies on the Chinese medicine treatment published in traditional Chinese medical journals on CTS through the CNKI search. Fifteen published studies between 2015 and 2020 were chosen and examined for the year of publication, sample size, study design type, diagnosis and evaluation of diverse criteria, treatment period, purpose of the study, and classification based on the treatment technique.
Results Out of 73 studies, 15 had practiced various Chinese medical treatments, such as acupuncture, moxibustion, manipulation, herbal medicine application therapy, and external herbal treatment.
Conclusions Various studies have investigated the Chinese medicine treatment for CTS in China. To envelope the treatment of CTS in Korean medicine, steady and valuable therapies for high-level clinical research are required. In the future, this study could be helpful in the development of the treatment of CTS with Korean medicine. (J Korean Med Rehabil 2020;30(4):119-132)

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1연안해역에서 석유오염물질의 세균학적 분해에 관한 연구

(2006)홍길동 외 1명심리학41회 피인용

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